Scientist - ADC Biology
Summary:
Client is seeking a Scientist (non-PhD) to join their ADC Biology team.
The Scientist- ADC Biology will be a key driver in advancing next-generation ADC technologies through collaborative, cross-functional research that spans from early discovery to pre-clinical development.
Responsibilities:
Apply cellular, biochemical, immunological, and molecular biology laboratory techniques to preclinical research projects in the areas of Cancer signaling and Cancer biology
Investigate MOAs of our therapeutics through the development, optimization, and execution of complex assays
Interact and collaborate with other functional groups across research
Provide leadership within the technical area of expertise; may train, direct, or mentor others
Design and execute key experiments to investigate novel therapeutic targets and MOAs of novel payloads to enable clear go/no-go decisions
Independently analyze data, document results, and present findings to large and small audiences
Maintain rigorous records of experimental progress using electronic laboratory notebooks
Present experimental results and scientific rationale to colleagues
Execute molecular, biochemical, and cell-based methodologies including cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling, multicolor flow cytometry, immunofluorescence, and live cell microscopy
Aid in the execution and analysis of additional experiments as needed within the ADC discovery research team
Qualifications:
Bachelor's degree in Cellular or Molecular Biology, Immunology, Biochemistry, or related field and 6+ years' relevant industry experience OR M.S. degree in Cellular or Molecular Biology, Immunology, Biochemistry, or related field with 4+ years' relevant industry experience
Experience with Microsoft Office (Excel, Word, PowerPoint) and analytical (Prism, FlowJo, etc.) software programs
Experience designing, performing, and interpreting complex experiments that require significant insight into problems being addressed, with some guidance
Working knowledge in specific areas of Cancer Biology and Cancer therapeutics, especially small molecule agents, Biologics, and ADCs
Experience working independently and working on multiple projects
Experience collaborating across teams and a variety of disciplines to provide experimental expertise and support others on joint projects
Experience leading parts of projects or initiatives within the area of expertise
Excellent written/oral communication skills with experience presenting/sharing details of the work with key stakeholders
Experience in experimental cancer biology, biochemical and/or immunological techniques (e.g., Cell culture, cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling, multicolor flow cytometry, immunofluorescent and live cell microscopy).
Background knowledge of the field of cell signaling and biochemistry
Experience developing complex cell and biochemical assays
Location/Schedule:
This is an on-site role based in Bothell, WA
Monday - Friday; 40 hours per week
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